Table 2.
miRNA | HHT1 | HHT2 | HHT (Pool) | Blood Sample | Reference |
---|---|---|---|---|---|
miRNA-370 | ↓ | ↔ | ND | Plasma | Present work |
miRNA-10a | ↔ | ↑ | ND | Plasma | Present work |
miRNA-28-5p | ND | ND | ↓ | PMNCs | Cannavicci et al., 2019 |
miRNA-361-3p | ND | ND | ↓ | PMNCs | Cannavicci et al., 2019 |
miRNA-210 | ND | ND | ↑ | Plasma | Zhang et al., 2013 |
miRNA-210 | ND | ND | (with PAVMs) | Plasma | Zhang et al., 2013 |
miRNA-27a | ↑ | ↑ | ↔ | Plasma | Tabruyn et al., 2013 |
miRNA-205 | ↓ | ↓ | (without PAVMs) | Plasma | Tabruyn et al., 2013 |
1 Total RNA from either plasma or peripheral mononuclear cells (PMNCs) was isolated, and levels of specific miRNAs were quantified, as indicated in the corresponding references. Increased (↑), decreased (↓), or unaffected (↔) levels of miRNAs are shown. HHT, hereditary hemorrhagic telangiectasia. ND, not determined.