Table 2.
MS (n = 16) | HC (n = 19) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Area | Mean | MD | SD | 25% Quartile | 75% Quartile | Mean | MD | SD | 25% Quartile | 75% Quartile | |
Test HbO [µmol/L] |
lDLPFC9 | 0.114 # | 0.090 | 0.214 | −0.001 | 0.135 | −0.083 | −0.081 | 0.217 | −0.204 | 0.056 |
rDLPFC9 | 0.055 # | −0.003 | 0.177 | −0.057 | 0.154 | −0.106 # | −0.075 | 0.222 | −0.283 | 0.025 | |
lDLPFC46 | 0.315 # | 0.304 | 0.207 | 0.212 | 0.351 | 0.104 | 0.074 | 0.257 | −0.086 | 0.332 | |
rDLPFC46 | 0.210 | 0.201 | 0.132 | 0.111 | 0.290 | 0.067 | 0.046 | 0.192 | −0.080 | 0.175 | |
mDLPFC9 | 0.067 | 0.034 | 0.155 | −0.050 | 0.180 | −0.113 # | −0.076 | 0.207 | −0.180 | −0.029 | |
lFPC10 | 0.122 | 0.072 | 0.237 | −0.036 | 0.218 | 0.008 | −0.034 | 0.225 | −0.141 | 0.185 | |
rFPC10 | 0.126 | 0.055 | 0.199 | 0.000 | 0.228 | 0.008 | −0.020 | 0.179 | −0.103 | 0.084 | |
mFPC10 | −0.058 | −0.074 | 0.250 | −0.265 | 0.081 | −0.131 | −0.188 | 0.189 | −0.213 | 0.051 | |
Test HbR [µmol/L] |
lDLPFC9 | −0.020 | −0.033 | 0.058 | −0.066 | 0.007 | 0.015 | 0.009 | 0.051 | −0.010 | 0.047 |
rDLPFC9 | −0.026 | −0.029 | 0.043 | −0.061 | −0.002 | 0.009 | 0.009 | 0.052 | −0.017 | 0.038 | |
lDLPFC46 | −0.047 | −0.028 | 0.061 | −0.086 | −0.008 | 0.011 | 0.004 | 0.074 | −0.040 | 0.061 | |
rDLPFC46 | −0.014 | 0.002 | 0.057 | −0.066 | 0.035 | 0.006 | 0.010 | 0.061 | −0.030 | 0.049 | |
mDLPFC9 | −0.055 | −0.055 | 0.065 | −0.114 | −0.001 | 0.000 | −0.006 | 0.056 | −0.031 | 0.030 | |
lFPC10 | −0.048 | −0.046 | 0.055 | −0.084 | 0.003 | −0.003 | 0.001 | 0.049 | −0.044 | 0.043 | |
rFPC10 | −0.023 | −0.038 | 0.058 | −0.067 | 0.020 | 0.011 | 0.002 | 0.064 | −0.037 | 0.038 | |
mFPC10 | −0.014 | −0.015 | 0.075 | −0.045 | 0.011 | −0.004 | 0.003 | 0.062 | −0.050 | 0.052 | |
Retest HbO [µmol/L] |
lDLPFC9 | 0.047 | 0.016 | 0.112 | −0.026 | 0.128 | −0.121 | −0.107 | 0.237 | −0.346 | 0.058 |
rDLPFC9 | 0.099 | 0.035 | 0.221 | −0.056 | 0.296 | −0.114 | −0.142 | 0.271 | −0.216 | 0.060 | |
lDLPFC46 | 0.215 | 0.227 | 0.169 | 0.122 | 0.331 | 0.055 | 0.045 | 0.202 | −0.066 | 0.244 | |
rDLPFC46 | 0.208 | 0.170 | 0.281 | 0.040 | 0.452 | 0.089 | 0.081 | 0.305 | −0.036 | 0.236 | |
mDLPFC9 | 0.086 | 0.100 | 0.157 | −0.046 | 0.215 | −0.114 | −0.119 | 0.258 | −0.224 | 0.073 | |
lFPC10 | 0.166 | 0.118 | 0.195 | 0.004 | 0.324 | −0.005 | 0.000 | 0.238 | −0.198 | 0.073 | |
rFPC10 | 0.130 | 0.138 | 0.149 | 0.029 | 0.229 | −0.031 | −0.009 | 0.187 | −0.107 | 0.071 | |
mFPC10 | −0.050 | −0.053 | 0.206 | −0.173 | 0.090 | −0.121 | −0.098 | 0.179 | −0.270 | −0.016 | |
Retest HbR [µmol/L] |
lDLPFC9 | 0.005 # | −0.028 | 0.070 | −0.034 | 0.052 | 0.029 | 0.020 | 0.057 | −0.014 | 0.058 |
rDLPFC9 | −0.028 | −0.031 | 0.040 | −0.067 | 0.008 | 0.010 | 0.008 | 0.076 | −0.043 | 0.078 | |
lDLPFC46 | −0.036 | −0.050 | 0.070 | −0.086 | 0.018 | 0.019 | 0.015 | 0.056 | −0.005 | 0.044 | |
rDLPFC46 | −0.081 # | −0.073 | 0.122 | −0.109 | 0.001 | 0.010 | 0.010 | 0.067 | −0.038 | 0.063 | |
mDLPFC9 | −0.054 | −0.054 | 0.048 | −0.108 | −0.016 | 0.016 | 0.012 | 0.050 | −0.013 | 0.051 | |
lFPC10 | −0.056 | −0.060 | 0.062 | −0.091 | −0.011 | 0.002 | 0.010 | 0.056 | −0.043 | 0.052 | |
rFPC10 | −0.049 | −0.042 | 0.054 | −0.088 | −0.008 | 0.000 | −0.008 | 0.069 | −0.035 | 0.034 | |
mFPC10 | −0.027 | −0.021 | 0.072 | −0.070 | 0.041 | 0.008 | 0.010 | 0.053 | −0.020 | 0.044 |
MS: multiple sclerosis; HC: healthy control; MD: median; SD: standard deviation; HbO: oxyhemoglobin; HbR: deoxyhemoglobin; l/r/mDLPFC9: left/right/medial dorsolateral prefrontal cortex Brodmann area 9; l/rDLPFC46: left/right dorsolateral prefrontal cortex Brodmann area 46; l/r/mFPC10: left/right/medial frontopolar cortex Brodmann area 10; #: not normally distributed.