Skip to main content
. 2020 Sep 17;10(9):643. doi: 10.3390/brainsci10090643

Table 4.

Bland and Altman limits of agreement, bias and confidence intervals of both groups (MS/HC).

Bland and Altman
(Test–Retest) 		Mean Area Under the Curve
Upper LoA Lower LoA Upper LoA Lower LoA
n Mean SD SE LoA Upper CI Lower CI LoA Upper CI Lower CI Mean SD SE LoA Upper CI Lower CI LoA Upper CI Lower CI
MS HbO
[µmol/L]		 rDLPFC9 16 −0.044 0.280 0.070 0.505 0.760 0.250 −0.592 −0.337 −0.847 −0.869 5.592 1.398 10.090 15.184 4.996 −11.829 −6.735 −16.923
lDLPFC9 16 0.067 0.219 0.055 0.497 0.696 0.297 −0.362 −0.163 −0.562 1.341 4.378 1.094 9.921 13.909 5.933 −7.239 −3.251 −11.227
rDLPFC46 16 0.003 0.339 0.085 0.667 0.976 0.358 −0.661 −0.353 −0.970 0.057 6.767 1.692 13.320 19.485 7.155 −13.207 −7.042 −19.372
lDLPFC46 16 0.099 0.282 0.071 0.652 0.909 0.395 −0.454 −0.197 −0.710 1.986 5.639 1.410 13.039 18.176 7.901 −9.067 −3.930 −14.204
mDLPFC9 16 −0.020 0.174 0.044 0.322 0.481 0.163 −0.361 −0.203 −0.520 −0.395 3.486 0.871 6.437 9.613 3.262 −7.227 −4.052 −10.403
lFPC10 16 −0.044 0.266 0.066 0.477 0.719 0.235 −0.565 −0.323 −0.807 −0.879 5.309 1.327 9.526 14.363 4.690 −11.285 −6.449 −16.122
rFPC10 16 −0.005 0.208 0.052 0.403 0.592 0.213 −0.412 −0.223 −0.601 −0.419 3.545 0.886 6.529 9.759 3.300 −7.368 −4.138 −10.597
mFPC10 16 −0.008 0.299 0.075 0.578 0.851 0.306 −0.593 −0.321 −0.866 −0.152 5.967 1.492 11.543 16.978 6.107 −11.847 −6.411 −17.283
MS HbR
[µmol/L]		 rDLPFC9 16 0.002 0.046 0.012 0.092 0.134 0.050 −0.088 −0.046 −0.130 0.043 0.920 0.230 1.845 2.683 1.008 −1.759 −0.921 −2.597
lDLPFC9 16 −0.025 0.072 0.018 0.116 0.181 0.050 −0.165 −0.100 −0.230 −0.497 1.431 0.358 2.308 3.612 1.004 −3.302 −1.998 −4.605
rDLPFC46 16 0.067 0.117 0.029 0.297 0.404 0.190 −0.163 −0.056 −0.270 1.342 2.344 0.586 5.937 8.073 3.802 −3.253 −1.117 −5.388
lDLPFC46 16 −0.010 0.062 0.016 0.112 0.169 0.055 −0.133 −0.076 −0.189 −0.206 1.246 0.312 2.237 3.373 1.102 −2.649 −1.513 −3.785
mDLPFC9 16 −0.001 0.056 0.014 0.109 0.161 0.058 −0.112 −0.060 −0.163 −0.021 1.128 0.282 2.189 3.216 1.162 −2.231 −1.204 −3.258
lFPC10 16 0.008 0.057 0.014 0.120 0.172 0.068 −0.104 −0.052 −0.156 0.156 1.142 0.285 2.394 3.434 1.354 −2.081 −1.041 −3.121
rFPC10 16 0.026 0.054 0.014 0.133 0.182 0.083 −0.080 −0.031 −0.130 0.485 0.910 0.228 2.269 3.098 1.440 −1.299 −0.469 −2.128
mFPC10 16 0.013 0.077 0.019 0.164 0.234 0.094 −0.138 −0.068 −0.208 0.258 1.543 0.386 3.283 4.688 1.877 −2.766 −1.360 −4.172
HC HbO
[µmol/L]		 rDLPFC9 19 0.008 0.244 0.056 0.486 0.689 0.282 −0.469 −0.265 −0.673 0.168 4.869 1.117 9.712 13.782 5.641 −9.375 −5.304 −13.445
lDLPFC9 19 0.038 0.162 0.037 0.356 0.492 0.220 −0.280 −0.144 −0.416 0.763 3.243 0.744 7.119 9.829 4.408 −5.592 −2.882 −8.303
rDLPFC46 19 −0.022 0.241 0.055 0.451 0.653 0.249 −0.495 −0.294 −0.697 −0.444 4.822 1.106 9.007 13.038 4.976 −9.895 −5.864 −13.926
lDLPFC46 19 0.049 0.236 0.054 0.512 0.710 0.315 −0.414 −0.217 −0.612 0.979 4.723 1.084 10.237 14.186 6.288 −8.278 −4.330 −12.227
mDLPFC9 19 0.000 0.260 0.060 0.511 0.728 0.293 −0.510 −0.292 −0.728 0.006 5.206 1.194 10.209 14.562 5.857 −10.198 −5.846 −14.550
lFPC10 19 0.013 0.207 0.048 0.419 0.593 0.246 −0.393 −0.220 −0.567 0.262 4.144 0.951 8.384 11.849 4.920 −7.861 −4.397 −11.326
rFPC10 19 0.038 0.182 0.042 0.396 0.548 0.243 −0.319 −0.167 −0.471 0.244 3.039 0.697 6.201 8.742 3.660 −5.713 −3.172 −8.254
mFPC10 19 −0.010 0.164 0.038 0.311 0.448 0.174 −0.331 −0.194 −0.468 −0.196 3.272 0.751 6.218 8.954 3.483 −6.610 −3.874 −9.345
HC HbR
[µmol/L]		 rDLPFC9 19 −0.011 0.052 0.012 0.092 0.136 0.048 −0.114 −0.070 −0.157 −0.214 1.049 0.241 1.842 2.719 0.965 −2.270 −1.393 −3.147
lDLPFC9 19 −0.014 0.051 0.012 0.085 0.128 0.043 −0.114 −0.071 −0.156 −0.285 1.015 0.233 1.704 2.552 0.855 −2.274 −1.426 −3.122
rDLPFC46 19 −0.004 0.063 0.015 0.120 0.173 0.067 −0.128 −0.075 −0.181 −0.083 1.267 0.291 2.400 3.459 1.341 −2.565 −1.506 −3.624
lDLPFC46 19 0.001 0.072 0.017 0.142 0.203 0.082 −0.140 −0.080 −0.201 0.019 1.443 0.331 2.846 4.052 1.640 −2.809 −1.603 −4.015
mDLPFC9 19 −0.016 0.057 0.013 0.096 0.144 0.048 −0.128 −0.080 −0.175 −0.316 1.140 0.262 1.918 2.871 0.965 −2.551 −1.598 −3.504
lFPC10 19 −0.005 0.045 0.010 0.084 0.122 0.046 −0.094 −0.056 −0.132 −0.103 0.907 0.208 1.674 2.432 0.916 −1.880 −1.122 −2.638
rFPC10 19 0.011 0.061 0.014 0.131 0.182 0.080 −0.109 −0.058 −0.160 0.133 0.981 0.225 2.055 2.875 1.235 −1.790 −0.970 −2.610
mFPC10 19 −0.012 0.064 0.015 0.113 0.166 0.059 −0.137 −0.084 −0.191 −0.247 1.275 0.292 2.251 3.317 1.186 −2.745 −1.680 −3.811
Bland and Altman
(Test–Retest) 		Slope Coefficient
Upper LoA Lower LoA
n Mean SD SE LoA upper CI lower CI LoA upper CI lower CI
MS HbO
[µmol/L]		 rDLPFC9 16 0.167 0.329 0.082 0.812 1.111 0.512 −0.478 −0.178 −0.777
lDLPF9 16 0.385 0.225 0.056 0.826 1.031 0.621 −0.055 0.149 −0.260
rDLPFC46 16 −0.014 0.417 0.104 0.803 1.183 0.423 −0.831 −0.452 −1.211
lDLPFC46 16 0.179 0.394 0.099 0.952 1.311 0.593 −0.594 −0.235 −0.953
mDLPFC9 16 0.028 0.404 0.101 0.818 1.186 0.451 −0.763 −0.396 −1.131
lFPC10 16 0.022 0.247 0.062 0.506 0.731 0.281 −0.461 −0.236 −0.686
rFPC10 16 −0.041 0.269 0.067 0.486 0.731 0.241 −0.568 −0.323 −0.813
mFPC10 16 −0.033 0.296 0.074 0.547 0.817 0.278 −0.613 −0.343 −0.883
MS HbR
[µmol/L]		 rDLPFC9 16 −0.108 0.049 0.012 −0.012 0.033 −0.057 −0.205 −0.160 −0.249
lDLPFC9 16 −0.105 0.073 0.018 0.038 0.104 −0.029 −0.248 −0.182 −0.315
rDLPFC46 16 0.062 0.144 0.036 0.345 0.477 0.213 −0.221 −0.090 −0.353
lDLPFC46 16 −0.015 0.103 0.026 0.186 0.280 0.093 −0.217 −0.123 −0.311
mDLPFC9 16 0.009 0.115 0.029 0.233 0.338 0.129 −0.216 −0.112 −0.321
lFPC10 16 −0.018 0.072 0.018 0.123 0.189 0.058 −0.159 −0.093 −0.224
rFPC10 16 0.022 0.054 0.014 0.128 0.177 0.079 −0.085 −0.035 −0.134
mFPC10 16 0.013 0.098 0.025 0.205 0.294 0.116 −0.179 −0.090 −0.269
HC HbO
[µmol/L]		 rDLPFC9 19 0.065 0.120 0.027 0.300 0.400 0.200 −0.169 −0.069 −0.270
lDLPF9 19 −0.029 0.129 0.030 0.224 0.331 0.116 −0.281 −0.173 −0.388
rDLPFC46 19 −0.107 0.305 0.070 0.490 0.745 0.236 −0.704 −0.449 −0.959
lDLPFC46 19 0.046 0.312 0.071 0.656 0.917 0.396 −0.565 −0.305 −0.826
mDLPFC9 19 −0.071 0.284 0.065 0.486 0.724 0.248 −0.629 −0.391 −0.867
lFPC10 19 0.010 0.245 0.056 0.490 0.694 0.285 −0.469 −0.265 −0.674
rFPC10 19 −0.018 0.154 0.035 0.284 0.413 0.155 −0.320 −0.191 −0.449
mFPC10 19 −0.001 0.198 0.045 0.387 0.552 0.221 −0.388 −0.223 −0.553
HC HbR
[µmol/L]		 rDLPFC9 19 0.008 0.042 0.010 0.090 0.125 0.055 −0.074 −0.039 −0.109
lDLPF9 19 0.012 0.043 0.010 0.097 0.133 0.060 −0.073 −0.037 −0.110
rDLPFC46 19 −0.016 0.083 0.019 0.147 0.216 0.077 −0.180 −0.110 −0.249
lDLPFC46 19 −0.023 0.069 0.016 0.114 0.172 0.055 −0.159 −0.101 −0.217
mDLPFC9 19 0.006 0.074 0.017 0.151 0.213 0.089 −0.140 −0.078 −0.202
lFPC10 19 −0.009 0.070 0.016 0.128 0.186 0.070 −0.145 −0.087 −0.203
rFPC10 19 −0.005 0.045 0.010 0.084 0.121 0.046 −0.093 −0.055 −0.130
mFPC10 19 −0.021 0.054 0.012 0.085 0.131 0.040 −0.128 −0.082 −0.173

MS: multiple sclerosis; HC: healthy control; CI: confidence interval; SD: standard deviation; SE: standard error; LoA: limits of agreement; HbO: oxyhemoglobin; HbR: deoxyhemoglobin; l/r/mDLPFC9: left/right/medial dorsolateral prefrontal cortex Brodmann area 9; l/rDLPFC46: left/right dorsolateral prefrontal cortex Brodmann area 46; l/r/mFPC10: left/right/medial frontopolar cortex Brodmann area 10.