Table 3.
Surgery characteristics.
| TMA (n = 15) | Non-TMA (n = 54) | OR | 95% CI | ||||
|---|---|---|---|---|---|---|---|
| Surgery type * | n (%) | n (%) | |||||
| Aortic valve repair | 3 | (20.0) | 13 | (24.1) | 0.78 | (0.19–3.23) | |
| w/o aortic replacement | |||||||
| Mitral valve | 3 | (20.0) | 15 | (27.8) | 0.65 | (0.16–2.63) | |
| Tricuspid valve | 3 | (20.0) | 11 | (20.4) | 0.97 | (0.23–4.08) | |
| Aortic replacement with or w/o aortic valve procedure | 9 | (60.0) | 17 | (31.5) | 3.26 | (1.0013–10.64) | |
| Aortocoronary bypass | 3 | (20.0) | 13 | (24.1) | 0.79 | (0.19–3.23) | |
| Heart transplantation | 0 | (0.0) | 4 | (7.4) | 0.00 | NA | |
| Postoperative interventions | |||||||
| Postoperative v-a ECMO | 2 | (13.3) | 22 | (40.7) | 0.22 | (0.05–1.09) | |
| Multiple surgeries (2 or more) | 9 | (60.0) | 31 | (57.4) | 1.11 | (0.34–3.56) | |
| Intraoperative characteristics | |||||||
| HCA | 7 | (46.7) | 17 | (31.5) | 1.9 | (0.59–6.11) | |
| Aortic cross-clamping | 13 | (86.7) | 43 | (79.6) | 1.6 | (0.33–8.48) | |
| Median (IQR) | Median (IQR) | p-value | |||||
| CPB time (min) | 230 | (156–272) | 190 | (145–243) | 0.299 | ||
| Cross-clamp time (min) # | 161 | (109–181) | 121 | (74.5–144) | 0.048 | ||
| HCA time (min) Δ | 26 | (22–35) | 59 | (54–75) | 0.003 | ||
| SACP time (min) Δ | 22 | (21–35) | 59 | (44–75) | 0.005 | ||
| Lowest core temperature (°C) | 32 | (25–35) | 33.5 | (25.5–35.5) | 0.413 | ||
| SACP temperature (°C) Δ | 22 | (22–23) | 22 | (22–22.3) | 0.820 | ||
All displayed valve procedures include valve replacement and/or repair. Abbreviations: v-a ECMO: veno-arterial extracorporeal membrane circulation. CPB: cardiopulmonary bypass. HCA: hypothermic circulatory arrest. SACP: selective antegrade cerebral perfusion. w/o: without. NA: not applicable. * Some patients underwent multiple procedures in one surgery. Δ Only patients undergoing HCA intraoperatively were included in this analysis. # Only patients undergoing aortic cross-clamping intraoperatively were included in this analysis.