Figure 7.

D-ornithine and its target protein Trypanosoma brucei ornithine decarboxylase (pdb id 1njj). (a) Ornithine decarboxylase chains A (red) and B (blue) are depicted as ribbons, with D-ornithine and G-418 as green and dark green molecules, respectively. (b) Ornithine decarboxylase chains A and B are depicted as hydrophobicity surface, with D-ornithine and G-418 as green and dark green molecules, respectively. (c) Ornithine decarboxylase chain A depicted as a transparent hydrophobicity surface, with SAGNM predictions are yellow atoms, and with D-ornithine and G-418 as green and dark green molecules. (d) D-ornithine and G-418 molecules depicted as colored bonds and sticks, correspondingly to the atom type and inside pockets on the surface of ornithine decarboxylase.