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. 2020 Aug 3;8(3):433. doi: 10.3390/vaccines8030433

Figure 4.

Figure 4

SV-specific T-cell responses in vivo. Mice were subcutaneously immunized with the SV alone, SV plus LNP, SV plus LNP-CpG, or SV plus alum on days 0 and 21. On day 28, splenocytes were cultured in the presence or absence of the SV in vitro. After 1 (for IL-2) or 5 (for IFN-γ and IL-13) days, the levels of IL-2, IFN-γ, and IL-13 were measured by using ELISA. n = 5 per group. Data are means ± SD. †††† p < 0.0001 vs. group immunized with the SV alone; **** p < 0.0001, as indicated by Tukey’s test.