Table 3.
Insulin Traits | Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
β | SE | p | β | SE | p | β | SE | p | β | SE | p | β | SE | p | |
Indices of insulin secretion | |||||||||||||||
HOMA-ß | 0.026 | 0.109 | 0.816 | 0.020 | 0.077 | 0.795 | 0.035 | 0.079 | 0.663 | 0.068 | 0.073 | 0.355 | 0.039 | 0.075 | 0.605 |
Stumvoll index | 0.000 | 0.001 | 0.540 | 0.000 | 0.000 | 0.486 | 0.000 | 0.000 | 0.606 | 0.000 | 0.000 | 0.993 | 0.000 | 0.000 | 0.923 |
Insulinogenic index 30′ | 1.731 | 8.883 | 0.846 | −1.613 | 5.893 | 0.785 | −4.068 | 5.574 | 0.469 | −3.810 | 5.562 | 0.497 | −2.840 | 6.268 | 0.653 |
Insulinogenic index 60′ | 11.858 | 8.787 | 0.183 | 5.398 | 6.427 | 0.405 | 4.670 | 6.084 | 0.446 | −2.496 | 5.883 | 0.674 | −3.227 | 6.025 | 0.595 |
Indices of insulin sensitivity | |||||||||||||||
HOMA-IS | −9.835 | 16.762 | 0.559 | −9.260 | 11.869 | 0.438 | −8.596 | 11.957 | 0.475 | −8.370 | 10.850 | 0.444 | −5.824 | 13.911 | 0.677 |
Raynaud index | 7.307 | 7.116 | 0.307 | 5.247 | 4.718 | 0.269 | 3.877 | 4.763 | 0.418 | 1.947 | 4.477 | 0.665 | 2.133 | 4.527 | 0.639 |
1/fasting insulin | 42.089 | 40.987 | 0.307 | 30.225 | 27.174 | 0.269 | 22.332 | 27.437 | 0.418 | 11.216 | 25.786 | 0.665 | 12.283 | 26.075 | 0.639 |
Matsuda index | 0.959 | 0.971 | 0.327 | 1.801 | 0.619 | 0.005 | 1.560 | 0.630 | 0.016 | 1.359 | 0.581 | 0.022 | 1.633 | 0.612 | 0.010 |
Abbreviations: V/S: Visceral/subcutaneous (fat volume ratio), ACCI: Age-adjusted Charlson comorbidity index. Footnotes: Data from the overall cohort are presented as beta coefficients (i.e., the median difference in PMV between each post-pancreatitis group and healthy controls group) and standard errors, from linear regression models. Statistically significant (p < 0.05) differences are shown in bold. Model 1: Unadjusted model; Model 2: Adjusted for age and sex; Model 3: Adjusted for age, sex, V/S fat volume ratio, and physical activity; Model 4: Adjusted for age, sex, V/S fat volume ratio, physical activity, smoking status, and alcohol consumption; Model 5: Adjusted for age, sex, V/S fat volume ratio, physical activity, smoking status, alcohol consumption, ACCI, pancreatic amylase, and use of insulin. Statistically significant (p < 0.05) associations are shown in bold.