Age at diagnosis of type 2 diabetes in adults with 22q11.2 deletion syndrome compared to the Canadian population.
Plotted are prevalence ratios (PR, as %, bar graphs: red, 22q11.2DS; blue, Canadian population) and 95% confidence intervals (CI, vertical lines) per age group for age at diagnosis of type 2 diabetes (T2D). Asterisks (*) indicate a statistically significant difference between the two groups. The proportion of those diagnosed with type 2 diabetes for the 22q11.2DS group was significantly greater in the 25–44 year age group (PR=2·38, 95% CI=1·39–4·08), and significantly lower in the 45–64 year age group (PR=0·54, 95% CI=0·31–0·97), than in the population. Of the two individuals in the 22q11.2DS group in the 65–69 year age range, neither had T2D diagnosed. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)