Vinyl ether PE structures that were differentially expressed in mouse brain lysosomes exposed to TBI. Analysis of ether PE lipids by UPLC-HDMSE as described for purified cortical lysosomes from sham and TBI at 1 h after injury. Abundance was plotted as mean SEM, N = 4, significance determined using a student t-test, *p < 0.05, ** ±p < 0.01, ***p < 0.005, ****p < 0.0001.