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Major Trichuris vaccine candidates.
| Antigen/adjuvant | Vaccine type | Protection % (Reduction in worm burden) | References |
|---|---|---|---|
| ES/FIA | Crude | 97% | (85) |
| EVs and EVs fractions | Crude | Significant reduction (% was not indicated) | (276) |
| rPP2A/OVS | r-protein | 97.90% | (277) |
| • rTm-WAP49/Montanide ISA 720 • rTm-WAP-F8+Na-GST-1/Montanide ISA 720 |
r-protein | • 48% • 38% |
(91) |
| VLPs expressing Trichuris T-cell epitopes | Epitope-based | 50% | (79) |
OVS, Oleic-vinyl sulfone; FIA, Freund's incomplete adjuvant.
