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In vivo permeability measurements and effect on Goblet cells and mucus production in LGI model. For in vivo measurements of gut permeability, animals were orally gavaged with FITC-dextran (A). Percentage of positive cells stained with AB (Alcian Blue) and mucus layer thickness measured by muc-2 immunohistochemistry (B,C). Control non-inflamed (vehicle-PBS), control inflamed (DNBS-PBS), B. bifidum CNCM I-4319 strain (DNBS-CNCM-I4319). *: p < 0.05 **: p < 0.01.
