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. 2020 Sep 8;12(9):2043. doi: 10.3390/polym12092043

Table 9.

Summary of selected applications of micro- and nanocellulose-based scaffolds.

Material Application & Advantages Reference
Collagen/oxidized MCC Microcellulose improved the haemostasis of the scaffolds without affecting its cytotoxicity. [220]
MFC/gelatine nanocomposite films Improved strength and flexibility of the films, which could be used in drug delivery. [221]
Micro-Nano structures of cellulose-collagen Significantly enhanced the uniform and distribution of cells, with good mechanical properties, may serve as an alternative material platform for bone regeneration. [222]
MFC/carboxymethyl chitosan hydrogel The strength, porosity and the work of fracture increased, providing a promising platform for tissue engineering scaffold. [223]
Alginate/CNF scaffold Use in tissue engineering. CNF enhances mechanical properties and makes it possible to tailored porosity and swelling behaviour. [224]
Collagen/CNF hydrogel scaffold The addition of CNF to collagen scaffold improved its mechanical properties with no effect on cell viability. [225]
PLA/CNF composite membrane CNF improved the crystalline ability of the membrane, thermal stability and mechanical properties. Hydrophilicity was also increased. [226]
NCC/gelatine/hyaluronic acid composite hydrogel NCC enhanced rheology and swelling results and the other properties. The cells attached, grew, and proliferated better than the control, giving the composite a great potential for the skin wound repair. [157]
Double crosslinking CNF hydrogel scaffolds Wound healing and tissue repair. Increase in the rigidity of scaffold enhances cell proliferation. [149]