Table 2.

Median values of bacterial loads (in ge/mL) and interquartile ranges (IQR) of all bacterial strains measured by the POC compatible qPCR assay and iai PadoTest, separated into groups. Statistically significant differences in group comparisons (healthy versus caries, healthy versus periodontitis, caries versus periodontitis) are marked with stars; * 0.05 > p ≥ 0.01, ** 0.01 > p ≥ 0.001, *** p < 0.001).

		Healthy		Caries		Periodontitis		p-Value
Panel	Strain	Median	IQR	Median	IQR	Median	IQR	Healthy-Caries	Healthy-Periodontitis	Caries-Periodontitis
POC compatible qPCR Assay	P. gingivalis	193,889	537,489	334,152	1,007,053	948,848	2,519,962	0.232	<0.001 ***	0.064
	T. forsythia	244,480	404,683	360,430	806,900	635,674	839,909	0.053	<0.001 ***	0.154
	T. denticola	11,025	9815	36,482	44,387	30,683	51,061	0.007 **	0.011 *	0.638
	F. nucleatum	239,745	316,713	252,436	321,205	366,993	541,370	0.319	0.004 **	0.081
	C. rectus	29,311	64,630	41,116	60,922	82,206	195,432	0.068	<0.001 ***	0.059
	P. intermedia	83,001	192,885	146,802	376,529	185,607	989,823	0.107	0.012 *	0.472
	A. actinomycetemcomitans	49,966	35,481	20,173	67,154	37,932	28,284	1.000	1.000	1.000
	S. mutans	22,218	72,897	194,821	1,305,829	68,350	871,276	<0.001 ***	0.004 **	0.004 **
	S. sobrinus	55,417	-	231,463	380,989	185,138	569,481	0.510	0.680	0.680
	Genus Lactobacilli	2,478,206	6,090,513	11,086,039	38,167,335	11,247,675	53,562,778	0.065	0.021*	0.894
iai PadoTest	A. actinomycetemcomitans	-	-	-	-	-	-	-	-	-
	T. forsythia	87,500	150,000	450,000	175,000	300,000	525,000	0.140	0.050	0.510
	P. gingivalis	50,000	25,000	25,000	12,500	75,000	112,500	0.235	0.011 *	0.011 *
	T. denticola	125,000	150,000	100,000	93,750	200,000	362,500	0.432	0.130	0.016 *
	P. intermedia	162,500	556,250	125,000	287,500	275,000	206,250	0.820	0.820	0.400
	F. alocis	75,000	150,000	75,000	118,750	100,000	275,000	1.000	1.000	1.000
	Universal Primer	671,500,000	1,136,250,000	873,000,000	1,317,000,000	744,000,000	1,055,500,000	0.350	0.720	0.720