ACT |
adoptive cell transfer |
APC |
antigen presenting cell |
aAPC |
artificial antigen presenting cell |
AdCAR |
adaptor CAR-T cell |
BiTE |
bi-specific T cell engager |
CAR |
chimeric antigen receptor |
CSF-1R |
colony-stimulating factor 1 receptor |
CTLA-4 |
cytotoxic T lymphocyte-associated antigen 4 |
DAMP |
danger-associated molecular pattern |
ECM |
extracellular matrix |
GETs |
genetically engineered T cells |
HLA |
human leukocyte antigen |
ICD |
immunogenic cell death |
ICI |
immune checkpoint inhibitor |
IL-2 |
interleukin-2 |
LDH |
lactate dehydrogenase A |
MDA-5 |
melanoma differentiation-associated protein 5 |
MDSC |
myeloid-derived suppressor cell |
NGMS |
next generation mutanome sequencing |
PD-1/PD-L1 |
programmed cell death protein 1 pathway |
PEG |
polyethylene glycol |
RNA-LPX |
RNA-lipoplex |
ROS |
reactive oxygen species |
scFv |
single-chain variable fragment |
siRNA |
small interfering RNA |
TAA |
tumor-associated antigen |
TAM |
tumor-associated macrophage |
TCR |
T cell receptor |
TGF-β1 |
transforming growth factor-β1 |
TIL |
tumor-infiltrating T lymphocyte |
TLR |
toll-like receptor |
TME |
tumor microenvironment, Treg, regulatory T cell |
TAA |
tumor-associated antigen |
UPR |
unfolded protein response |