Skip to main content
. 2020 Aug 20;8(9):1257. doi: 10.3390/microorganisms8091257

Figure 3.

Figure 3

Lactic fermentation of papaya pulp affects its antiviral activity against ZIKV. (a) A549 cells were incubated for 48 h with two-fold serial dilutions (125–4000 µg/mL) of extracts of papaya pulp fermented by L. plantarum 75, Lc. pseudomesenteroïdes 56 or W. cibaria 64. Unfermented papaya pulp extract was used as a positive control. Cell viability was assessed through the MTT assay. Results are means ± SD of four independent experiments and are expressed as relative value compared to non-treated cells. (b) A549 cells were infected with an input of ZIKVGFP of 2 PFU/cell in the presence of different concentrations (31–4000 µg/mL) of fermented papaya pulp extracts. Unfermented papaya pulp extract was used as a positive control. Flow cytometric analysis of GFP fluorescence was performed 24 h post-infection. The results shown are means ± SD of three independent experiments and are expressed as relative value compared to untreated infected cells.