Figure 2.

Heat maps of CpG density patterns (Sample A1 and Sample C1 as representative samples for aestivation and control groups). CpG density (x-axis) is defined as the number of CpG dinucleotides in 200 bp windows. The methylation level (y-axis) is defined as the average methylation level of cytosines in CpGs. The thin black lines denote the median methylation level of CpGs at the given local density. The red color gradient indicates an abundance of CpGs that fall into bins of given methylation levels and CpG densities. The blue bar charts show the distribution of CpG densities. The green bar charts show the distribution of methylation levels.