Skip to main content
. 2020 Sep 3;11(9):1043. doi: 10.3390/genes11091043

Figure 3.

Figure 3

mTORC1 promotes protein synthesis. Decreased protein synthesis correlates with extension of lifespan and many mutants affected in translation initiation, elongation, and ribosomal proteins are long-lived. Some of the proposed mechanisms whereby less translation could promote longevity are illustrated.