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. 2020 Sep 13;9(9):2093. doi: 10.3390/cells9092093

Figure 3.

Figure 3

Effect of curcumin on LD and dLAN-exposed animals (a) hippocampal region showing CA3 pyramidal neurons (b) cerebral region showing cortex neurons. In dLAN exposed groups, higher numbers of pyknotic and chromatolysis neurons were seen in the hippocampal CA3 region as well as cortex region (shown by red arrows). Curcumin treatment had significantly reduced the pyknotic and chromatolysis neurons in a dose-dependent manner. More number of normal pyramidal and cortex neurons can be seen in the curcumin treated and LD groups (shown by black arrows). PPN: pyknotic pyramidal neurons; CPN: chromatolysis pyramidal neurons; PCN: pyknotic cortex neuron; CCN: chromatolysis cortex neuron; NPN: normal pyramidal neurons; NCN: normal cortex neurons; dLAN: dim light at night; LD: light (12 h)/dark (12 h).