Relative abundance of genes involved in the microbial nitrogen (A) and sulfur (B) cycle in the six depths examined in the Mariana Trench. NifDKH, nitrogenase molybdenum-iron protein; amoABC, methane/ammonia monooxygenase; hao, hydroxylamine dehydrogenase; narGHI, nitrate reductase; napAB, nitrate reductase; nirKS, nitrite reductase; norBC, nitric oxide reductase; nosZ, nitrous oxide reductase; narB, ferredoxin nitrate reductase; nasAB, assimilatory nitrate reductase; nirA, ferredoxin-nitrite reductase; nirB, nitrite reductase (NADH) large subunit; nirD, nitrite reductase (NADH) small subunit; nrfA, nitrite reductase (cytochrome c-552); nrfH, cytochrome c nitrite reductase small subunit; K20932, hydrazine synthase subunit; hdh, hydrazine dehydrogenase. sat, sulfate adenylyltransferase; cysNC, bifunctional enzyme CysN/CysC; cysD, sulfate adenylyltransferase subunit 2; cysN, sulfate adenylyltransferase subunit 1; cysJ, sulfite reductase (NADPH) flavoprotein alpha-component; cysI, sulfite reductase (NADPH) hemoprotein beta-component; sir, sulfite reductase (ferredoxin); aprAB, adenylylsulfate reductase; dsrAB, dissimilatory sulfite reductase; soxABCDXYZ, thiosulfate oxidation by SOX complex; doxD, thiosulfate dehydrogenase (quinone) large subunit; tsdA, thiosulfate dehydrogenase; ETHE1, sulfur dioxygenase; sorB, sulfite dehydrogenase; soeABC, sulfite dehydrogenase; fccAB, sulfide dehydrogenase.