Table 2.
Correlation between hemogram and Wnt signaling expression in AML blast cells. Spearman analysis was used to assess the correlation between Wnt protein levels in blast cells and parameters of the hemogram, including (A) white blood cells (WBC); (B) Hemoglobin (Hb), and (C) platelets (PLTS). Statistical significance when p ≤ 0.05.
| (A) White Blood Cells (WBC) | ||||||||
| WBC | GSK3α | GSK3β | Non-Phospho-β-catenin | Total β-Catenin | Phospho-GSK-3α (Ser 21) | Phospho-GSK3β (Ser 9) | Ser33/37/Thr41-Phospho- β-Catenin | Ser675-Phospho-β-Catenin |
| r | 0.1117 | 0.3236 | 0.3205 | 0.2317 | 0.1109 | 0.2414 | 0.4311 | 0.4106 |
| p value | 0.2583 | 0.0271 | 0.0284 | 0.0870 | 0.2597 | 0.0780 | 0.0043 | 0.0064 |
| (B) Hemoglobin (Hb) | ||||||||
| Hb | GSK3α | GSK3β | Non-Phospho-β-Catenin | Total β-Catenin | Phospho-GSK-3α (Ser 21) | Phospho-GSK3β (Ser 9) | Ser33/37/Thr41-Phospho- β-Catenin | Ser675-Phospho-β-Catenin |
| r | −0.02664 | −0.02471 | 0.09962 | 0.002832 | 0.1640 | 0.2041 | 0.1749 | 0.2092 |
| p value | 0.4387 | 0.4431 | 0.2816 | 0.4935 | 0.1696 | 0.1162 | 0.1538 | 0.1104 |
| (C) Platelets (PLTS) | ||||||||
| PLTS | GSK3α | GSK3β | Non-Phospho-β-Catenin | Total β-Catenin | Phospho-GSK-3α (Ser 21) | Phospho-GSK3β (Ser 9) | Ser33/37/Thr41-Phospho- β-Catenin | Ser675-Phospho-β-Catenin |
| r | 0.2725 | 0.2478 | 0.4430 | 0.1463 | 0.2366 | 0.3473 | 0.3730 | 0.4452 |
| p value | 0.0539 | 0.0726 | 0.0034 | 0.1972 | 0.0824 | 0.0190 | 0.0125 | 0.0033 |