TABLE 1.
Comparisons of RNA packaging efficiencies from mutants with the same number of G-to-A substitutions
| Mutant | No. of Gs mutated | RNA packaging efficiency (% of WT) | P value compared to the most defective mutant in the groupa |
|---|---|---|---|
| 3way2 | 4 | 96.2 ± 5.4 | <0.0001 |
| 3*site | 4 | 74.5 ± 6.3 | <0.0001 |
| 1site | 4 | 60.0 ±2.8 | |
| 2,3*site | 7 | 40.5 ± 4.8 | <0.0001 |
| 3way1 | 7 | 33.8 ± 5.3 | <0.0001 |
| 1,2site | 7 | 15.1 ± 1.9 | |
| 3way1,2 | 11 | 17.4 ± 4.0 | <0.0001 |
| 1,2,3*site | 11 | 2.9 ± 0.9 |
a
P values were determined using unpaired one-way ANOVA with Bonferroni adjustment.