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The ectodomain length of EphA2 is important for EBV fusion activity. (A) Schematic drawing of the EphA2, EphA4, and, EphA2/EphA4 chimeras. LBD, ligand-binding domain; CYS, cysteine-rich region; FN, fibronectin region. (B) EBV fusion with HEK293T cells transfected with control plasmid pcDNA3.1, EphA2, EphA4, or EphA2/EphA4 chimeras, as indicated. The fusion activity of HEK293T cells transfected with pcDNA 3.1 was set to 100%.
