FIG 1.

Cell viability and density dependency for intercellular BoDV-1 dynamics. Viabilities of OL, OL/itEBLN, and OL/BoDV cells were evaluated and are expressed as the means + five independent experiments in panel A. BoDV dynamics in OL cells are shown in panel B. Dots show the time course of experimental data for the numbers of uninfected cells (blue) and infected cells (red). The shaded region corresponds to 95% posterior predictive intervals, and the solid lines yield the mean for the full mathematical model with best-fit parameter estimates. Using all accepted MCMC parameter estimates from the time course experimental data sets, the distribution of $e^{-\alpha }$ is shown in panel C. n.s., no significance (t test).