Figure 1.

Frequency distribution of the CATT microsatellite repeat (rs3063368) and the G>C SNP (rs755622) in patients with AKI versus patients not affected by AKI after cardiac surgery. (A) In patients with AKI, the frequency of the GC genotype and the CATT₇ allele is higher than in patients without AKI (Χ² test for trend, p = 0.001). (B) The AKI event rate was higher in patients with the GC genotype (20%) versus patients with the CC or the GG genotype (13%), and higher in CATT₇ carriers (23%) compared to non-carriers. (C) Patients carrying the GC genotype or the CATT₇ allele had a significantly increased relative risk of AKI compared to all other patients.