Table 4.
Analysis of the variations of the primary outcome measures within the post-COVID-19 according to the other examined variables. The drugs and clinical complications occurred during the hospital recovery are listed.
| Variable | RPCP Flow Index Means ± SD (CI) |
p | RPCP Perfusion Index Means ± SD (CI) |
p |
|---|---|---|---|---|
| Age | R = −0.421 Slope = −340.216 Intercept = 207.199 |
<0.001 | R = −0.278 Slope = −145.568 Intercept = 116.528 |
0.01 |
| Sex | M = 0.453 ± 0.02 (0.448–0.458) F = 0.454 ± 0.02 (0.449–0.460) |
0.70 | M = 0.435 ± 0.03 (0.425–0.444) F = 0.441 ± 0.03 (0.432–0.450) |
0.39 |
| Systemic arterial hypertension | Absent = 0.457 ± 0.01 (0.453−0.461) Present = 0.442 ± 0.02 (0.433–0.451) |
<0.001 | Absent = 0.439 ± 0.03 (0.432–0.446) Present = 0.431 ± 0.04 (0.413–0.449) |
0.31 |
| Systemic autoimmune or inflammatory diseases | Absent = 0.453 ± 0.02 (0.449–0.457) Present = 0.455 ± 0.02 (0.447–0.463) |
0.68 | Absent = 0.437± 0.03 (0.429–0.444) Present = 0.439 ± 0.03 (0.425–0.453) |
0.75 |
| Diabetes | Absent = 0.453 ± 0.02 (0.448–0.458) Present = 0.454 ± 0.02 (0.448–0.459) |
0.91 | Absent = 0.433 ± 0.03 (0.424–0.442) Present = 0.442 ± 0.03 (0.432–0.453) |
0.17 |
| Axial myopia > 1D | Absent = 0.453 ± 0.02 (0.449–0.458) Present = 0.454 ± 0.01 (0.447–0.462) |
0.87 | Absent = 0.438 ± 0.03 (0.430–0.446) Present = 0.434 ± 0.02 (0.422–0.446) |
0.68 |
| IOP in study examination | R = 1.28 Slope = 41.712 Intercept = 10.553 |
0.53 | R = 2.83 Slope = 57.931 Intercept = 4.006 |
0.61 |
| Red/dry eye during infection | Absent = 0.453 ± 0.02 (0.448–0.459) Present = 0.454 ± 0.02 (0.449–0.459) |
0.87 | Absent = 0.436 ± 0.03 (0.427–0.446) Present = 0.438 ± 0.03 (0.429–0.448) |
0.78 |
| Hydroxychloroquine | No = 0.455 ± 0.02 (0.449–0.462) Yes = 0.453 ± 0.02 (0.448–0.457) |
0.57 | No = 0.442 ± 0.03 (0.431–0.453) Yes = 0.435 ± 0.03 (0.427–0.444) |
0.36 |
| Lopinavir + ritonavir | No = 0.457 ± 0.01 (0.453–0.461) Yes = 0.447 ± 0.02 (0.439–0.455) |
0.01 | No = 0.443 ± 0.03 (0.435–0.450) Yes = 0.425 ± 0.03 (0.413–0.438) |
0.01 |
| Darunavir + ritonavir | No = 0.451 ± 0.02 (0.445–0.457) Yes = 0.457 ± 0.01(0.453–0.461) |
0.10 | No = 0.433 ± 0.03 (0.424–0.443) Yes = 0.442 ± 0.03 (0.433–0.452) |
0.19 |
| Heparin | No = 0.454 ± 0.02 (0.450–0.458) Yes = 0.453 ± 0.020(0.445–0.460) |
0.71 | No = 0.438 ± 0.03 (0.430–0.446) Yes = 0.435 ± 0.03 (0.422–0.448) |
0.68 |
| Antiplatelet therapy | No = 0.455 ± 0.02 (0.451–0.458) Yes = 0.43 ± 0.02 (0.409–0.450) |
0.0036 | No = 0.439 ± 0.03 (0.433–0.445) Yes = 0.404 ± 0.06 (0.343–0.464) |
0.0026 |
| Corticosteroids | No = 0.454 ± 0.02 (0.450–0.457) Yes = 0.453 ± 0.03 (0.419–0.486) |
0.89 | No = 0.438 ± 0.03(0.431–0.444) Yes = 0.425 ± 0.05 (0.374–0.476) |
0.43 |
| ICU admission | No = 0.454 ± 0.02 (0.450–0.458) 0.02 Yes = 0.449 ± 0.01(0.438–0.461) |
0.57 | No = 0.437 ± 0.03 (0.430–0.444) Yes = 0.44 ± 0.02 (0.424–0.456) |
0.84 |
| NIV treatment | No = 0.453 ± 0.02 (0.449–0.457) Yes = 0.461 ± 0.02 (0.444–0.479) |
0.22 | No = 0.438 ± 0.03 (0.431–0.445) Yes = 0.43 ± 0.02 (0.413–0.448) |
0.55 |
| Pulmonary embolism | No = 0.453 ± 0.02 (0.449–0.457) Yes = 0.47 ± 0.01 (0.450–0.490) |
0.16 | No = 0.438 ± 0.03 (0.431–0.445) Yes = 0.414 0.372–0.457 0.030 |
0.3 |
| Venous thrombosis | No = 0.453 ± 0.02 (0.449–0.457) Yes = 0.476 ± 0.005 (0.470–0.483) |
0.054 | No = 0.438 ± 0.03 (0.431–0.445) Yes = 0.417 ± 0.03 (0.369–0.466) |
0.37 |
RPCP = radial peripapillary capillary plexus; IOP = Intraocular pressure; ICU = Intensive care unit; NIV = noninvasive ventilation.