Table 1.
Expression of membrane transporters in human cancers.
| SLC1A5 (ASCT2) | SLC6A14 (ATB0,+) | SLC7A1-2-3 (CAT 1-2-3) | SLC7A5 (LAT1) | SLC7A11 (xCT) | SLC38A2 (SNAT2) | References |
|---|---|---|---|---|---|---|
| PCA | PCA | PCA | PCA | [19,61,62,63,64,65,66,67] | ||
| CRC | CRC | CRC (C1-2) | CRC | CRC | [19,61,67,68,69,70,71,72,73,74,75] | |
| HCC | HCC (C1) | HCC | HCC | [61,69,76,77] | ||
| LC | LC | LC | [19,61,67,78,79,80,81] | |||
| BC | BC | BC (C1) | BC | BC | BC | [19,26,61,62,67,69,79,82,83,84,85,86,87,88,89,90,91] |
| N & G | N & G | [61,92,93] | ||||
| EC | EC | [61,94,95] | ||||
| OC | OC | OC | [19,61,96,97] | |||
| RCC | RCC | [19,61,98,99] | ||||
| P & BC | P & BC | PC | PC | [61,100,101,102,103,104] | ||
| GC | GC (C1) | GC | [61,105,106,107,108,109,110] | |||
| BT | [111] | |||||
| PM (C1) | [61] | |||||
| CC | CC | CC | CC | [19,86,112,113] | ||
| OSCC | OSCC | OSCC | [114,115,116,117] | |||
| TC (C1) | [118] | |||||
| M (C1) | M | [119,120] | ||||
| L (C1-2) | L | [121,122,123,124] | ||||
| ESCA | ESCA | ESCA | [115,125] | |||
| G | [88,126,127,128,129] | |||||
| THCA | [130] | |||||
| LSCC | [131] | |||||
| GBM | [132,133] | |||||
| THCA (C3) | [130] | |||||
| OC (C3) | TSCC | [134,135] |
PCA: Prostate cancer; CRC: Colorectal cancer; HCC: Hepatocellular carcinoma; LC: Lung cancer; BC: Breast cancer; N & G: Neuroblastoma and glioma; EC: Endometrioid carcinoma; OC: Ovaric cancer; RCC: Renal cell carcinoma; P & BC: Pancreatic and biliary cancer; PC: Pancreatic cancer; GC: Gastric cancer; BT: brain tumor; PM: Pleural mesothelioma; CC: Cervical cancer; OSCC: Oral squamous cell carcinoma; TC: Thymic cancer; M: melanoma; L: Leukemia; ESCA: Esophageal cancer; G: Glioma; THCA: Thyroid carcinoma; LSCC: Laryngeal squamous cell carcinoma; GBM: Glioblastoma; TSCC: tongue squamous cell carcinoma. In parentheses: C1, CAT1; C2, CAT2; C3, CAT2.