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cLSM images of SiNCs-encapsulated siRNA Cy5, co-localized with lysosomes in CD8+ T-cells after 17 h. A co-localization assay was performed by staining lysosomes with LysoTracker dye (red). The membrane was stained with CellMask™Orange (blue). The SiNC was labeled with siRNA Cy5 (green). The merged images demonstrated that the SiNCs encapsulated siRNA Cy5 were co-localized with lysosomes, as indicated by the white arrows. The scale bars represent 10 μm.
