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. 2020 Jul 14;8(3):384. doi: 10.3390/vaccines8030384

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Experiment 2: Kinetics of total Ig and isotype profile of antibodies against S. suis serotype 7 or serotype 9 in piglets from either vaccinated or non-vaccinated sows. Randomly selected 120 piglets (3 piglets/sow, for a total of 60 piglets/group) from vaccinated and non-vaccinated sows were originally included in the serological study. Nevertheless, nine piglets from three different non-vaccinated sows could not be identified, for a total of 51 piglets finally enrolled for serology in this group. Piglets were sampled at one, three and five weeks of age and total Ig [IgG + IgM] titers were determined by ELISA against S. suis serotype 7 (A) or serotype 9 (B). Piglets were sampled at one week to evaluate titers of IgG1 against S. suis serotype 7 (C) or serotype 9 (D) and titers of IgG2 against S. suis serotype 9 (E). Antibody titers for individual piglets are shown with horizontal bars representing mean ± SEM. Values significantly different are shown in the graph with corresponding p value.