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. 2020 Aug 31;9(9):2004. doi: 10.3390/cells9092004

Figure 1.

Figure 1

Process of DNA methylation. DNA methyltransferases (DNMT1, DNMT3A, and DNMT3B) catalyze the transfer of a methyl group from the universal methyl donor S-adenosylmethionine (SAM), resulting in the formation of 5-methylcytosine.