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Immunized mice survival after a lethal challenge with pathogenic influenza A viruses in comparison to that of the negative control (pcDNA3.1). (a–c) Infection with virus A/California/4/09 (H1N1pdm); (d–f) infection with virus A/Aichi/2/68 (H3N2); (a,d) DNA vaccinated, (b) and (e) H1N1 vaccinated, and (c,f) H3N2 vaccinated.
