Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 25;9(9):1959. doi: 10.3390/cells9091959

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Proteomics comparison of AD, MCI and CTRL CSF-derived EV protein: (A) Venn diagram showing the number of proteins reproducibly identified among the three separate TMT-MS. (B) Enrichment of brain cell-specific markers in CSF-derived EV proteins and brain-derived EV proteins. Yellow: Neuron, Green: Microglia, Blue: Astrocytes, Orange: Oligodendrocytes. The parentheses show the number of identified cell type-specific proteins. (C) Comparison of the cell type-specific proteins in AD CSF-derived EVs, MCI EVs and CTRL EVs. The left panel shows AD vs. MCI. The red bar shows higher expression in AD compared with MCI and the green bar indicates higher expression in MCI compared with AD. The middle panel indicates AD vs. CTRL. The red bar shows higher expression in AD compared with CTRL and the blue bar indicates higher expression in CTRL compared with AD. The right panel shows MCI vs. CTRL. The green bar shows higher expression in MCI compared with CTRL and the blue bar indicates higher expression in CTRL compared with MCI.