Table 1.
For Label-Free Proteomics | AD | |||||
(n = 3) | ||||||
Age, mean | 82.7 ± 7.57 | |||||
Gender | 2M, 1F | |||||
For TMT-Label Proteomics | CTRL | MCI | AD | t-test a (p-value b) | t-test a (p-value b) | t-test a (p-value b) |
(n = 10) | (n = 10) | (n = 10) | (CTRL_MCI) | (CTRL_AD) | (MCI_AD) | |
Age, mean | 89.8 ± 6.12 | 89.0 ± 5.27 | 87.1 ± 4.41 | 0.313 (0.758) | 1.131 (0.273) | 0.874 (0.393) |
Gender c | 5M, 5F | 5M, 5F | 5M, 5F | |||
PMI, mean | 2.90 ± 0.85 | 2.94 ± 0.87 | 2.84 ± 0.49 | −0.106 (0.917) | 0.173 (0.865) | 0.299 (0.768) |
Braak stage | 2.8 ± 0.42 | 3.3 ± 0.67 | 5.4 ± 0.52 | −1.987 (0.062) | −12.333 (<0.001) | −7.814 (<0.001) |
a The group comparisons were performed using independent t-test. b The statistical significance of the differences were calculated using a two-tailed test. c M: Male, F: Female.