Table 1.
Baseline characteristics. ∗Only the first case per patient was included in this part of the table. †This includes all 10 cases, including the two patients who presented twice for cerebral bypass surgery. ETCO2, end-tidal carbon dioxide; IQR, inter-quartile range.
| Preoperative characteristics | Patients (N=8)∗ | ||
|---|---|---|---|
| Gender (%) | Female | 5 (62.5) | |
| Age (yr, median [IQR]) | 48 [41–53] | ||
| BMI (kg m−1, median [IQR]) | 29 [26–35] | ||
| ASA physical status (%) | 1 | 0 (0.0) | |
| 2 | 2 (25.0) | ||
| 3 | 5 (62.5) | ||
| 4 | 1 (12.5) | ||
| Ischaemic heart disease (%) | 0 (0.0) | ||
| Heart failure (%) | 0 (0.0) | ||
| Cerebrovascular accident (%) | Ischaemic | 8 (100.0) | |
| Haemorrhagic | 0 (0.0) | ||
| Diabetes mellitus (%) | No | 7 (87.5) | |
| Non-insulin dependent | 0 (0.0) | ||
| Insulin dependent | 1 (12.5) | ||
| Hypertension (%) | 4 (50.0) | ||
| Vascular disease (%) | No | 5 (62.5) | |
| Peripheral | 0 (0.0) | ||
| Central | 3 (32.5) | ||
| Elevated creatinine level (%) | 0 (0.0) | ||
| Anticoagulants (%) | 8 (100.0) | ||
| Beta blocking agents (%) | 1 (12.5) | ||
| Renin–angiotensin–aldosterone system inhibitors (%) | 2 (25.0) | ||
| Calcium antagonist (%) | 1 (12.5) | ||
| Diuretics (%) | 0 (0.0) | ||
| Statins (%) | 5 (62.5) | ||
| Indication for cerebral bypass (%) | Moyamoya disease | 5 (62.5) | |
| Carotid occlusion | 3 (37.5) |
||
|
Intraoperative characteristics |
Patients (N = 8)∗ |
Cases (N = 10) † |
|
| Duration of surgery (min, median [IQR]) | 299 [260–357] | 297 [260–342] | |
| pH before start of study (mm Hg, median [IQR]) | 7.39 [7.38–7.40] | 7.39 [7.38–7.40] | |
| Paco2 before start of study (mm Hg, median [IQR]) | 5.2 [4.8–5.2] | 5.2 [4.8–5.2] | |
| ETCO2 before start of study (mm Hg, median [IQR]) | 4.8 [4.5–4.9] | 4.8 [4.5–4.9] | |
| Haemoglobin before start of study (g dl−1, median [IQR]) | 11.4 [9.8–12.1] | 11.4 [10.0–11.9] | |
| Haematocrit before start of study (%, median [IQR]) | 34 [29–35] | 34 [30–35] | |
| Baseline MAP before induction of anaesthesia (mm Hg, median [IQR]) | 98 [96–101] | 98 [93–105] | |