Figure 1.

Representative images of perigonadal white adipose tissue (WAT) cross-sections (A) stained with hematoxylin–phloxine–saffron (HPS) and WAT weight of different adipose tissue depots (B) from Ldlr−/−.Leiden mice fed a healthy chow diet or fed a high-fat diet (HFD) containing lard or a fast food diet (FFD) containing milk fat for 28 weeks. Perigonadal WAT inflammation was analyzed by measuring the number of crown-like-structures (CLS)/mm² (C). Values represent mean ± SEM for ≥8 mice per group. ** p < 0.01 and *** p < 0.001 vs. chow; # p < 0.05 and ### p < 0.001 FFD vs. HFD.