Figure 2.

Binding of the wild-type (wt) peptide to importin α3 (Impα3) monitored by spectroscopic techniques: (A) Fluorescence spectrum obtained by excitation at 280 nm of the complex between Impα3 and the wt peptide and the addition spectrum obtained by the sum of the spectra of both isolated macromolecules. (B) Far-UV CD (ultraviolet circular dichroism) spectrum of the complex between the Impα3 and wt peptides and the additional spectrum obtained by the sum of the spectra of both isolated macromolecules.