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. 2020 Sep 18;11(9):1094. doi: 10.3390/genes11091094

Table 1.

List of different classes of polyphenols, primary sources, their content based on weight and serving and their respective molecular functions.

Polyphenols Polyphenol
Source
Polyphenol Content Based on Weight or Volume
(mg/kg wt or mg/L)
Molecular Functions References
Phenolic acids/Hydroxybenzoic acids
Gallic acid Berries, pineapples, bananas, lemons and wines 40–130 Anti-oxidative, pro-oxidative, anti-inflammatory, antibacterial, antiviral, anti-melanogenic, anti-invasive and anti-proliferative [47,48,49,50,51]
Ellagic acid Berries, pomegranate, walnuts and pecans Anti-oxidative, anti-inflammatory, anti-angiogenic, antimetastatic, anti-proliferative and anti-invasive [47,52,53]
Phenolic acids/Hydroxycinnamic acids
Caffeic acid Kiwifruit 600–1000 Anti-diabetic,
anti-carcinogenic, protective effects against UVB-induced skin damage, interleukin-10 and activation of mitogen-activated protein kinase (MAPK)
[54,55,56]
Rosmarinic acid Herbs Anti-oxidative, reduction of HCA formation and modulation of epigenetic changes [47,53,57]
Ferulic acid Aubergine 600–660 Anti-oxidative, anti-inflammatory, antibacterial, antimicrobial, antiallgergic, hepatoprotective and antiviral [58]
Chlorogenic acid Cherry 180–1150 Anti-oxidative, antimicrobial,
anti-inflammatory, antibacterial, analgesic and antipyretic
[59,60]
Flavonoids
Myricetin Broccoli 40–100 Anti-oxidative, anti-inflammatory, anti-allergic properties, analgesic property, hepatoprotective and hypouricemic activities, anti-diabetic and anti-obesity properties [61,62,63,64,65]
EGCG Tea, apples, grapes,
berries, red wine and chocolate
Anti-oxidative, anti-proliferative, suppression of growth and invasion, antiangiogenic, anti-inflammatory, inhibition of telomerase activity and lipid peroxidation and modulation of estrogen activity [66,67,68,69,70,71]
Apigenin Grapefruit, parsley, onion, orange, tea and wheat 20–140 Anti-oxidative, anti-mutagenic, anti-inflammatory, anti-viral, inhibition of tumor growth, anti-invasive, and anti-proliferative [48,72,73,74]
Quercetin Onions, broccoli,
apples, apricots, berries, nuts, seeds, tea, wine and cocoa
Anti-oxidative, tumor inhibition, anti-proliferative, antimetastatic, anti-angiogenic and inhibition of lipid peroxidation [67,70,71,72,75,76,77]
Genistein Miso 250–900 Anti-oxidative, anti-invasive, anti-inflammatory, anti-metastatic, delay/repression of tumor development/growth and anti-proliferative [67,70,71,72]
Stilbenes
RES Red wine, grapes, berries and peanuts Anti-oxidative, anti-inflammatory, anti-proliferative and anti-estrogenic [75,77,78,79,80,81,82]
PTER Anti-oxidative, anti-inflammatory, anti-proliferative and modulation of lipid metabolism [75,77,78,80,81,82]

EGCG—Epigallocatechin gallate, RES—Resveratrol, PTER—Pterostilbene.