Figure 1.

Differential Expression Patterns of pri-miR-18a and Mature miR-18a in sPE Placentas

(A–D) Quantitative real-time PCR experiments were performed to measure the expression levels of pri-miR-18a (A and B) and mature miR-18a (C and D) in the chorionic plates (A and C) and basal plates (B and D) of the placentas derived from sPE patients (n = 13) and normal pregnant women (n = 32). Data are presented as mean ± SD. ∗p < 0.05. (E) miR-18a expression levels change across gestation. At least 3 samples were collected and analyzed in each gestational week. Data are presented as mean ± SD. ∗Compared to the miR-18a level at gestational weeks 6–7 (6–7w), p < 0.05.