Table 2.

Cell growth inhibition (GI₅₀) in μg/mL of EHGP and EHGV for inhibition of cell proliferation in cancer cell lines (A2780, ES2, A549, H460) and normal cells (HUVEC).

Time	Sample	Cell Line
		A2780	ES2	H460	A549	HUVEC
48 h	EHGV	313.6 μg/mL	133.1 μg/mL	105.4 μg/mL	105.4 μg/mL	113,300 μg/mL
	EHGP	177.4 μg/mL	51.4 μg/mL	360.6 μg/mL	1122 μg/mL	40,650 μg/mL
72 h	EHGV	16.92 μg/mL	137.7 μg/mL	56.51 μg/mL	22.64 μg/mL	5537 μg/mL
	EHGP	196 μg/mL	64.83 μg/mL	311.9 μg/mL	551.1 μg/mL	indeterminate

EHGV = hydroethanolic geopropolis extract of M. fasciculata from Viana city, Maranhão State, Brazil; EHGP = hydroethanolic geopropolis extract of M. fasciculata from Pinheiro city, Maranhão State, Brazil; GI₅₀ values calculated by non-linear regression equation log (inhibitor) versus response—variable slope by the MTT assay. Concentration required to inhibit cell growth by 50% as determined by the dose response curve. Values are expressed as mean ± standard deviation of cytotoxicity assays (n = 4).