. 2020 Oct 12;6(10):e05137. doi: 10.1016/j.heliyon.2020.e05137

Table 6.

Effect of chlorogenic acid on the writhing responses to assess the neuropathic pain in Wistar albino rats.

S. No.	Treatment Type	Number of Writhing Responses
S. No.	Group Type	(2^nd week)	(4^th week)	(8^th week)	(12^th week)
1	Normal Control	15.41 ± 2.31	12.21 ± 2.02	10.13 ± 1.70	8.4 ± 1.21
2	Diabetic Control	25.11 ± 0.22^a	26.86 ± 1.58^a	27.39 ± 0.52^a	29.13 ± 0.34^a
3	Standard	21.14 ± 1.78	24.13 ± 1.18∗∗∗	23.44 ± 0.91∗∗∗	18.54 ± 0.45∗∗∗
4	Treated 1	21.19 ± 0.36	22.64 ± 1.31∗∗∗	22.41 ± 2.91∗∗∗	16.52 ± 0.71∗∗∗
5	Treated 2	20.17 ± 2.91	21.28 ± 2.91∗∗∗	20.17 ± 2.91∗∗∗	14.81 ± 1.31∗∗∗

Values are expressed as Mean ± SEM; n = 6. One-way ANOVA; Tukey-Kramer multiple comparisons test: ^aP< 0.001 in comparison with normal control; and ∗∗∗P < 0.001 in comparison with the diabetic control.