Table 7.
Effect of chlorogenic acid on Cold hyperalgesia: Acetone drop test in wistar albino rats.
| S. No. | Treatment Type |
Cold Hyperalgesia (Acetone drop test) |
|||
|---|---|---|---|---|---|
| Group Type | Allodynia Score in sec (2nd week) | Allodynia Score in sec (4th week) | Allodynia Score in sec (8th week) | Allodynia Score in sec (12th week) | |
| 1 | Normal Control | 4.91 ± 0.19 | 4.13 ± 1.34 | 4.19 ± 2.03 | 4.62 ± 1.42 |
| 2 | Diabetic Control | 7.77 ± 3.23a | 8.11 ± 1.23a | 8.75 ± 1.28a | 9.12 ± 0.71a |
| 3 | Standard | 5.28 ± 1.15 | 4.98 ± 0.25∗∗∗ | 4.37 ± 0.25∗∗∗ | 6.98 ± 2.93∗∗∗ |
| 4 | Treated 1 | 5.97 ± 2.02 | 5.11 ± 1.23∗∗∗ | 5.01 ± 3.15∗∗∗ | 4.91 ± 2.51∗∗∗ |
| 5 | Treated 2 | 4.93 ± 1.65 | 4.84 ± 0.26∗∗∗ | 4.76 ± 0.35∗∗∗ | 4.53 ± 3.61∗∗∗ |
Values are expressed as Mean ± SEM; n = 6. One-way ANOVA; followed by Tukey-Kramer multiple comparisons test: aP< 0.001 in comparison with normal control; ∗∗∗P < 0.001 in comparison with the diabetic control.