Table 8.
Effect of chlorogenic acid on Mechanical hyperalgesia: Pin prick test in wistar albino rats.
| Treatment Type |
Mechanical Hyperalgesia (Pin prick test) |
||||
|---|---|---|---|---|---|
| S. No. | Group Type | Response latency in sec (2nd week) | Response latency in sec (4th week) | Response latency in sec (8th week) | Response late Response latency in sec (12th week) |
| 1 | Normal Control | 2.13 ± 0.82 | 2.21 ± 0.16 | 1.99 ± 0.66 | 2.31 ± 0.31 |
| 2 | Diabetic Control | 6.16 ± 1.36a | 6.96 ± 1.04a | 7.71 ± 0.48a | 8.78 ± 1.04a |
| 3 | Standard | 6.86 ± 1.19 | 7.98 ± 1.02∗∗∗ | 8.92 ± 0.28∗∗∗ | 4.99 ± 0.37∗∗∗ |
| 4 | Treated 1 | 6.03 ± 0.64 | 7.79 ± 0.21∗∗∗ | 8.41 ± 1.39∗∗∗ | 4.16 ± 1.32∗∗∗ |
| 5 | Treated 2 | 6.44 ± 1.06 | 7.94 ± 1.23∗∗∗ | 4.05 ± 0.12∗∗∗ | 3.11 ± 0.62∗∗∗ |
Values are expressed as Mean ± SEM; n = 6. One-way ANOVA; Tukey-Kramer multiple comparisons test: aP< 0.001 in comparison with normal control; and ∗∗∗P < 0.001 in comparison with the diabetic control.