Table 3.
Whole sample (n = 296) | Cognitively healthy (CO + SCD + REL) (n = 190) | Cognitively healthy worrier (n = 100) | Cognitively healthy non-worrier (n = 88) | |
---|---|---|---|---|
Predictors | OR (95% CI), p value | OR (95% CI), p value | OR (95% CI), p value | OR (95% CI), p value |
Age | 1.002 (0.958–1.048), 0.921 | 1.028 (0.971–1.089), 0.343 | 1.019 (0.943–1.102), 0.631 | 1.015 (0.914–1.127), 0.787 |
Sex | 0.972 (0.583–1.621), 0.913 | 1.108 (0.560–2.191), 0.769 | 1.099 (0.434–2.782), 0.843 | 1.235 (0.397–3.847), 0.716 |
Education | 0.968 (0.888–1.056), 0.467 | 1.018 (0.911–1.137), 0.757 | 1.070 (0.924–1.238), 0.365 | 0.904 (0.729–1.121), 0.357 |
MEM | 0.597 (0.414–0.862), 0.006** | 0.486 (0.226–1.048), 0.066 | 0.662 (0.258–1.698), 0.391 | 0.293 (0.069–1.244), 0.096 |
Aß42 (pg/ml) | 0.999 (0.998–1.000), 0.030* | 1.000 (0.998–1.001), 0.353 | 0.999 (0.998–1.000), 0.124 | 1.001 (0.999–1.003), 0.180 |
t-tau (pg/ml) | 0.999 (0.996–1.001), 0.243 | 0.999 (0.995–1.003), 0.571 | 0.999 (0.994–1.004), 0.780 | 1.000 (0.993–1.000), 0.960 |
p-tau (pg/ml) | 1.013 (0.993–1.034), 0.211 | 1.011 (0.981–1.042), 0.482 | 1.017 (0.977–1.058), 0.409 | 0.987 (0.928–1.050), 0.688 |
Note: * p < .05, ** p < .01. Aβ42 beta-amyloid 42, CO healthy controls, CI confidence interval, MEM memory factor score, OR odds ratio, p-tau phospho-tau, REL first-degree relatives of AD patients, SCD subjective cognitive decline, t-tau total tau