TABLE 4.
Multivariate analysis of the factors associated with prognosis in children with high-risk neuroblastoma.
Variables | Classification | N | PFS | OS | ||
HR (95% CI) | p value | HR (95% CI) | p value | |||
AMC × ALC | ≥106 (/μl)2 | 17 | 1 | 1 | ||
<106 (/μl)2 | 13 | 3.97 (1.14–13.76) | 0.030 | 1.12 (0.27–5.31) | 0.813 | |
Hb | ≥10 g/dl | 15 | 1 | 1 | ||
<10 g/dl | 15 | 1.76 (0.49–6.30) | 0.383 | 1.39 (0.25–7.66) | 0.709 | |
Ferritin | <350 ng/ml | 21 | 1 | 1 | ||
≥350 ng/ml | 7 | 2.57 (0.52–12.78) | 0.248 | 4.40 (0.65–29.95) | 0.130 |
ALC, absolute lymphocyte counts; AMC, absolute monocyte count; CI, confidence interval; Hb, hemoglobin; HR, hazard ratio; OS, overall survival; and PFS, progression-free survival.