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. 2020 Aug 14;43(8):236–243. doi: 10.1097/CJI.0000000000000330

FIGURE 3.

FIGURE 3

A, Amount of TNF-α, IL-17A, IFN-γ, and IL-10 secreted by CD8+ T cells cultured with 1 µg/mL CD155 with/out anti-TIGIT antibody. B, Amount of IL-17A, IFN-γ, IL-10, perforin, granzyme B, and granlysin produced by stimulated CD8+ T cells cocultured with Bel-7402 with/out anti-TIGIT antibody. C, Flow cytometry plots showing CD155 expression in Bel-7402-vector or Bel-7402-CD155 RNAi cells. D, Amount of TNF-α, IL-17A, IFN-γ, IL-10, perforin, and granlysin produced by stimulated CD8+ T cells cocultured with Bel-7402-vector or Bel-7402-CD155 RNAi cells with/out anti-TIGIT antibody. *P<0.05; **P<0.01; ***P<0.001, ****P<0.0001. IFN indicates interferon; IL, interleukin; TIGIT, T-cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domain; TNF, tumor necrosis factor.