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. 2019 Dec 27;112(10):1055–1062. doi: 10.1093/jnci/djz243

Table 1.

Unadjusted characteristics of patients initiating TKIs for CML or immunomodulatory drugs for multiple myeloma by plan funding status and time before and after parity*

Characteristics CML cohort
Multiple myeloma cohort
Preparity
Postparity
Preparity
Postparity
Fully insured Self-funded Fully insured Self-funded Fully insured Self-funded Fully insured Self-funded
(n = 523) (n = 638) (n = 432) (n = 489) (n = 879) (n = 961) (n = 755) (n = 731)
Patient characteristics
Age category, y, %
 <45 40.3 38.6 36.3 35.4 8.8 8.1 7.3 8.8
 45–54 31.4 28.8 30.6 33.7 29.9 30.6 31.0 27.6
 55–64 28.3 32.6 33.1 30.9 61.3 61.3 61.7 63.6
 Sex, % female 43.6 45.3 39.4 42.1 40.5 42.0 40.9 41.6
Census-level SES, %
 Unemployed 5.6 5.6 5.5 5.6 5.6 5.7 5.3 5.2
 Black population 12.6 14.6 13.2 11.9 14.5 16.6 12.8 11.4
 Insured 86.7 86.5 85.9 86.7 86.3 86.6 87.3 87.6
 Under FPL 12.4 13.0 13.2 12.2 13.2 12.8 11.9 11.4
Drug initiated
 Brand imatinib 70.6 66.8 31.7 34.2
 Generic imatinib 13.9 12.5
 Dasatinib 16.4 16.9 29.9 33.1
 Nilotinib 13.0 16.3 24.5 20.3
 Lenalidomide 85.2 83.7 96.7 96.0
 Thalidomide 14.8 16.3 3.3 4.0
Year treatment initiated
 2008 17.4 16.9 17.5 18.7
 2009 22.4 18.0 21.1 21.4 0.3
 2010 15.9 16.8 0.2 0.8 15.1 17.4 0.9 1.1
 2011 14.2 15.7 1.9 3.3 15.8 16.8 3.3 4.4
 2012 9.8 13.8 13.0 10.0 12.2 11.4 10.9 9.0
 2013 9.2 8.5 10.7 12.7 9.2 7.8 9.8 11.8
 2014 9.6 7.5 13.0 10.6 7.2 5.6 10.9 10.8
 2015 1.7 2.7 18.3 18.2 1.9 0.8 18.3 20.1
 2016 0.2 25.0 20.9 26.4 26.4
 2017 18.1 23.5 19.6 16.1
High-deductible health plan member
 Yes 13.4 15.8 16.9 23.5 12.3 15.9 18.0 28.2
Quarter diagnosed
 Q1 21.4 24.5 32.9 37.4 22.1 19.6 25.8 32.8
 Q2 28.9 27.7 29.9 23.9 26.6 28.8 31.3 27.8
 Q3 26.0 24.0 19.0 19.0 28.7 26.9 20.5 17.5
 Q4 23.7 23.8 18.3 19.6 22.6 24.7 22.4 21.9
*

CML = chronic myeloid leukemia; FPL = federal poverty level; SES = socioeconomic status; TKI = tyrosine kinase inhibitor.