Table 1.
Characteristics | CML cohort |
Multiple myeloma cohort |
||||||
---|---|---|---|---|---|---|---|---|
Preparity |
Postparity |
Preparity |
Postparity |
|||||
Fully insured | Self-funded | Fully insured | Self-funded | Fully insured | Self-funded | Fully insured | Self-funded | |
(n = 523) | (n = 638) | (n = 432) | (n = 489) | (n = 879) | (n = 961) | (n = 755) | (n = 731) | |
Patient characteristics | ||||||||
Age category, y, % | ||||||||
<45 | 40.3 | 38.6 | 36.3 | 35.4 | 8.8 | 8.1 | 7.3 | 8.8 |
45–54 | 31.4 | 28.8 | 30.6 | 33.7 | 29.9 | 30.6 | 31.0 | 27.6 |
55–64 | 28.3 | 32.6 | 33.1 | 30.9 | 61.3 | 61.3 | 61.7 | 63.6 |
Sex, % female | 43.6 | 45.3 | 39.4 | 42.1 | 40.5 | 42.0 | 40.9 | 41.6 |
Census-level SES, % | ||||||||
Unemployed | 5.6 | 5.6 | 5.5 | 5.6 | 5.6 | 5.7 | 5.3 | 5.2 |
Black population | 12.6 | 14.6 | 13.2 | 11.9 | 14.5 | 16.6 | 12.8 | 11.4 |
Insured | 86.7 | 86.5 | 85.9 | 86.7 | 86.3 | 86.6 | 87.3 | 87.6 |
Under FPL | 12.4 | 13.0 | 13.2 | 12.2 | 13.2 | 12.8 | 11.9 | 11.4 |
Drug initiated | ||||||||
Brand imatinib | 70.6 | 66.8 | 31.7 | 34.2 | — | — | — | — |
Generic imatinib | — | — | 13.9 | 12.5 | — | — | — | — |
Dasatinib | 16.4 | 16.9 | 29.9 | 33.1 | — | — | — | — |
Nilotinib | 13.0 | 16.3 | 24.5 | 20.3 | — | — | — | — |
Lenalidomide | — | — | — | — | 85.2 | 83.7 | 96.7 | 96.0 |
Thalidomide | — | — | — | — | 14.8 | 16.3 | 3.3 | 4.0 |
Year treatment initiated | ||||||||
2008 | 17.4 | 16.9 | — | — | 17.5 | 18.7 | — | — |
2009 | 22.4 | 18.0 | — | — | 21.1 | 21.4 | — | 0.3 |
2010 | 15.9 | 16.8 | 0.2 | 0.8 | 15.1 | 17.4 | 0.9 | 1.1 |
2011 | 14.2 | 15.7 | 1.9 | 3.3 | 15.8 | 16.8 | 3.3 | 4.4 |
2012 | 9.8 | 13.8 | 13.0 | 10.0 | 12.2 | 11.4 | 10.9 | 9.0 |
2013 | 9.2 | 8.5 | 10.7 | 12.7 | 9.2 | 7.8 | 9.8 | 11.8 |
2014 | 9.6 | 7.5 | 13.0 | 10.6 | 7.2 | 5.6 | 10.9 | 10.8 |
2015 | 1.7 | 2.7 | 18.3 | 18.2 | 1.9 | 0.8 | 18.3 | 20.1 |
2016 | — | 0.2 | 25.0 | 20.9 | — | — | 26.4 | 26.4 |
2017 | — | — | 18.1 | 23.5 | — | — | 19.6 | 16.1 |
High-deductible health plan member | ||||||||
Yes | 13.4 | 15.8 | 16.9 | 23.5 | 12.3 | 15.9 | 18.0 | 28.2 |
Quarter diagnosed | ||||||||
Q1 | 21.4 | 24.5 | 32.9 | 37.4 | 22.1 | 19.6 | 25.8 | 32.8 |
Q2 | 28.9 | 27.7 | 29.9 | 23.9 | 26.6 | 28.8 | 31.3 | 27.8 |
Q3 | 26.0 | 24.0 | 19.0 | 19.0 | 28.7 | 26.9 | 20.5 | 17.5 |
Q4 | 23.7 | 23.8 | 18.3 | 19.6 | 22.6 | 24.7 | 22.4 | 21.9 |
CML = chronic myeloid leukemia; FPL = federal poverty level; SES = socioeconomic status; TKI = tyrosine kinase inhibitor.