Table 1.

All aDMRs Found Above the Threshold of .4% Average Methylation Change per Year, Including Those That Did Not Pass Significance Testing

Chromosome	Start Index	End Index	Methylation Change	Length	p Value	FWER	Annotation	EZH2 Binding	SUZ12 Binding	CTCF Binding
Chromosome 2	106015767	106015771	0.005309614	2	0	0	FHL2	Weak, displaced	None	Strong
Chromosome 6	11044877	11044888	0.004609445	2	0	0	ELOVL2	Strong	Weak	Strong
Chromosome 17	3379283	3379567	−0.004233153	2	0	0	ASPA	None	None	Weak
Chromosome 1	207997020	207997020	−0.006858645	1	0	0	MIR29B2CHG	None	None	Strong
Chromosome 15	31775895	31775895	0.005213145	1	0	0	OTUD7a	Strong	Weak	Weak
Chromosome 3	147126753	147126753	0.005123596	1	0.007491	0.0004	ZIC4	Strong	Weak	Weak
Chromosome 2	145116633	145116633	−0.004828198	1	0.037453	0.002
Chromosome 9	133908909	133908909	−0.004801037	1	0.037453	0.002
Chromosome 5	16179633	16179633	0.004699174	1	0.048689	0.0026
Chromosome 2	164590272	164590272	−0.004456642	1	0.146067	0.0078
Chromosome 14	94405681	94405681	0.00440554	1	0.17603	0.0092
Chromosome 5	95295740	95295740	−0.004379721	1	0.198502	0.0104
Chromosome 2	66654644	66654644	−0.004320193	1	0.277154	0.0142
Chromosome 19	16830749	16830749	−0.004301742	1	0.303371	0.0156
Chromosome 20	2730488	2730488	0.004195198	1	0.430712	0.0218
Chromosome 6	110736772	110736772	−0.004156555	1	0.509363	0.026
Chromosome 12	98151379	98151379	−0.004086738	1	0.674157	0.0344
Chromosome 6	105388694	105388694	0.004028017	1	0.898876	0.0462
Chromosome 1	206685423	206685423	−0.004024052	1	0.910112	0.0468
Chromosome 1	77907656	77907656	0.004003854	1	0.988764	0.0506

Note: Those that pass significance testing were annotated as to the most likely regulated gene and their transcription factor binding patterns.