Table 1.
Patient characteristics based on CX3CR1 genotype
| Characteristic | V/V, n (%) | V/I + I/I, n (%) |
|---|---|---|
| 45 | 45 | |
| Sex | ||
| Female | 19 (42) | 24 (53) |
| Male | 26 (58) | 21 (47) |
| Age at diagnosis, y, mean (SD) | 37.5 (12.2) | 38.1 (9.2) |
| KPS | ||
| 90 or 100 | 39 (87) | 42 (93) |
| <90 | 6 (13) | 3 (7) |
| Extent of resection | ||
| GTR | 11 (24) | 12 (27) |
| STR or biopsy | 34 (76) | 33 (73) |
| Adjuvant therapy | ||
| None | 12 (27) | 19 (42) |
| Radiation | 11 (24) | 12 (27) |
| Chemotherapy | 9 (20) | 9 (20) |
| Both | 13 (29) | 5 (11) |
| IDH1 mutation | ||
| No | 9 (20) | 10 (22) |
| Yes | 36 (80) | 35 (78) |
| 1p/19q codeletion* | ||
| No | 8 (30) | 10 (40) |
| Yes | 19 (70) | 15 (60) |
Abbreviations: GTR, gross total resection; IDH1, isocitrate dehydrogenase 1; SD, standard deviation; STR, subtotal resection; VV, homozygous for the common CX3CR1 V249 allele; V/I + I/I, heterozygous or homozygous for the variant CX3CR1 I249 allele.
*Only a subset of samples were analyzed for 1p/19q codeletion. None of the characteristics were significantly different between the 2 groups (unpaired t-test for age at diagnosis, chi-squared test for all others).