Table 2.

The Association of Repeated Measures of Risk Factors and Survival to 90+ in a Multiplicative Model

Exposure	Age-adjusted	Adjusted for Demographics	Adjusted for All Demographics and Medication Use
	OR (95% CI)
Systolic blood pressure—continuous†
SBP	0.79 (0.74, 0.85)***	0.79 (0.74, 0.85)***	0.79 (0.72, 0.88)***
Age × SBP	1.05 (1.03, 1.08)***	1.04 (1.02, 1.07)***	1.05 (1.01, 1.09)*
Diastolic blood pressure—spline†
DBP < 60	1.09 (1.06, 1.12)***	1.09 (1.07, 1.13)***	1.10 (1.03 1.17)
DBP ≥ 60	0.91 (0.88, 0.94)***	0.93 (0.90, 0.96)***	0.86 (0.78, 0.94)
LDL cholesterol—continuous†
LDL	1.17 (1.09, 1.26)***	1.13 (1.05, 1.22)***	1.14 (1.06, 1.24)**
Age × LDL	0.97 (0.95, 1.00)*	0.97 (0.95, 1.00)*	0.99 (0.97, 1.03)
HDL cholesterol—spline at 40 (men) or 50 (women)†
HDL < 40/50	1.46 (1.37, 1.55)***	1.30 (1.18, 1.42)***
HDL ≥ 40/50	0.97 (0.92, 1.02)	0.97 (0.92, 1.03)
Age × HDL < 40/50	0.96 (0.94, 0.99)**	0.97 (0.94, 0.99)**
BMI categories (ref = normal weight)
Underweight	0.37 (0.22, 0.65)**	0.32 (0.18, 0.56)***
Overweight	1.05 (0.90, 1.21)	1.15 (0.99, 1.34)
Obese	0.95 (0.78, 1.14)	1.01 (0.83, 1.22)
Glucose—continuous†
Glucose	0.62 (0.54, 0.70)***	0.66 (0.59, 0.75)***	0.63 (0.54, 0.72)***
Age × Glucose	1.06 (1.02, 1.10)**	1.06 (1.02, 1.10)**	1.08 (1.03, 1.13)**

Note: BMI = body mass index; CI = confidence interval; DBP = diastolic blood pressure; HDL = high-density lipoprotein; LDL = low-density lipoprotein; OR = odds ratio; SBP = systolic blood pressure.

*p < .05, **p < .01, ***p < .001.

^†All continuous predictors are shown per Z score, standardized to baseline visit mean and standard deviation.

Demographic adjusted model was adjusted for sex, black race, education level (<HS, HS/GED, >HS), and study site.