Table 1.

An example of the transformation process for “Acute dacryoadenitis of left eye”

Concept name	Acute dacryoadenitis of left eye
Representation ([c1, c2, c3])	[acute dacryoadenitis, of, left eye]
Replacement candidates for “acute dacryoadenitis” (r1)	{dacryoadenitis, inflammation of specific body systems, acute disease, acute inflammatory disease, inflammatory disorder, inflammatory disorder of head, disorder of eyelid or lacrimal system, disorder of lacrimal gland}
Replacement candidates for “left eye” (r3)	{organ of special sense, eye, subdivision of face}
Combinatorial replacements	[{acute dacryoadenitis, dacryoadenitis, inflammation of specific body systems, acute disease, acute inflammatory disease, inflammatory disorder, inflammatory disorder of head, disorder of eyelid or lacrimal system, disorder of lacrimal gland}, of, {left eye, organ of special sense, eye, subdivision of face}]
Potentially missing IS-A relations detected in source terminologies	SNOMEDCT_US: “acute dacryoadenitis of left eye” IS-A “acute disease of eye” MEDCIN: “acute dacryoadenitis of left eye” IS-A “inflammatory disorder of eye”

SNOMEDCT_US: SNOMED CT (U.S. version).