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. 2020 Apr 3;22(10):1474–1483. doi: 10.1093/neuonc/noaa077

Table 2.

Multivariate analysis of PFS among BRAF V600E mutant PLGGs

a. Multivariate Analysis of PFS among BRAF V600E Mutant PLGGs
Variable Hazard Ratio (HR) 95% CI for HR P-value
Low LUMP score 2.41 1.06–5.42 0.035
CDKN2A homozygous deletion 8.95 2.97–33.19 <0.0001
Non–hemispheric/cerebellar location 4.69 1.46–18.98 0.008
No gross total resection 1.05 0.37–2.83 0.91
Age <3 y 1.35 0.48–4.15 0.57
b. Multivariate Analysis of PFS among BRAF V600E Mutant PLGGs
Variable Hazard Ratio (HR) 95% CI for HR P-value
High lymphocytic infiltration 3.33 0.98–12.73 0.053
CDKN2A homozygous deletion 21.75 4.75–153.95 0.001
Non–hemispheric/cerebellar location 4.19 0.85–32.36 0.08
No gross total resection 1.30 0.32–4.76 0.68
Age <3 y 2.15 0.41–18.77 0.38