Table 2.
a. Multivariate Analysis of PFS among BRAF V600E Mutant PLGGs | |||
---|---|---|---|
Variable | Hazard Ratio (HR) | 95% CI for HR | P-value |
Low LUMP score | 2.41 | 1.06–5.42 | 0.035 |
CDKN2A homozygous deletion | 8.95 | 2.97–33.19 | <0.0001 |
Non–hemispheric/cerebellar location | 4.69 | 1.46–18.98 | 0.008 |
No gross total resection | 1.05 | 0.37–2.83 | 0.91 |
Age <3 y | 1.35 | 0.48–4.15 | 0.57 |
b. Multivariate Analysis of PFS among BRAF V600E Mutant PLGGs | |||
Variable | Hazard Ratio (HR) | 95% CI for HR | P-value |
High lymphocytic infiltration | 3.33 | 0.98–12.73 | 0.053 |
CDKN2A homozygous deletion | 21.75 | 4.75–153.95 | 0.001 |
Non–hemispheric/cerebellar location | 4.19 | 0.85–32.36 | 0.08 |
No gross total resection | 1.30 | 0.32–4.76 | 0.68 |
Age <3 y | 2.15 | 0.41–18.77 | 0.38 |